Inositol is a pseudovitamin found in cell membranes. It is necessary for cellular signaling and the growth of human cells.
Inositol supplements may help treat specific medical conditions, including some anxiety and fertility disorders. They may also have other health-promoting effects.
- May reduce anxiety disorders by affecting serotonin such as panic disorder, obsessive-compulsive disorder (OCD) and posttraumatic stress disorder (PTSD)
- Help reduce panic attacks
- May aid blood sugar control by improving insulin sensitivity
- May improve fertility in women
- Reduce symptoms of depression
- Supports mood
- Promotes healthy triglyceride levels
- Maintains osmotic balance in cells.
Inositol is a carbohydrate found in your body, as well as in food and dietary supplements.
There are various forms of this molecule, and each of them has a chemical structure similar to the main sugar found in your blood — glucose. It plays a role in many bodily processes. Therefore, it has been studied for its potential health benefits.
Inositol once belonged to the Vitamin B-complex but it is now considered a pseudovitamin because it is synthesized in the human body. It is a sugar alcohol that is also present in dietary sources such as corn, cereal, citrus fruits, legumes, and meats.
A typical dietary intake provides 1 g/day of Inositol. It is present in the highest concentration in the central nervous system tissues (CNS) and can be synthesized directly by the CNS. The kidneys can synthesize up to 4 g/day. Therapeutic doses of 6 g/day can increase cerebrospinal fluid concentrations of inositol by 70%.
Inositol includes 9 different stereoisomers: Myo-inositol, Epi-inositol, Allo-inositol, Cis-inositol, Muco-inositol, Neo-inositol, Scyllo-inositol, L-Chiro-inositol, and D-Chiro-inositol. The most common form in the body is myo-inositol which is over 90% of cellular inositol, and scyllo-inositiol is the next most abundant stereoisomer. Most supplements are formed from myo-inositol.
Myo-inositol is involved in the formation of cell membranes and a precursor for the phosphatidylinositol cycle. Cellular messengers such as diacylglycerol (which regulates some of the protein kinase C functions), inositol-1,4,5-triphosphate (which modifies calcium levels within the cells), and phosphatidylinositol-3,4,5-biphosphate (which is important for signal transduction) all require Myo-inositol as a precursor.
Myo-inositol’s concentration in the central nervous system (CNS) is very high and the tissues in the CNS can synthesize it as well. Myo-inositol functions as an osmolyte which can regulate the tonicity of cell fluid volume. Inadequate levels of myo-inositol have been tied to imbalances in brain chemistry affecting mood and genetic pathologies.
Inositol Capsules provide 500 mg per 1 capsule. Suggested use for adults is 1 capsule by mouth daily, or as directed by your healthcare practitioner.
Inositol Side Effects and Toxicity
Inositol is generally well tolerated. Side effects may include diarrhea, nausea, headache, fatigue, and dizziness. Rarely, side effects may include insomnia, tics, allergy symptoms, thirst, and agitation. Toxicity information is insufficient at this time.
If you are taking any medications, please consult with your healthcare practitioner before beginning supplementation with Inositol.