Party Recovery Complex is formulated with ingredients to help you recover from the unwanted effects of alcohol consumption and hangovers.
Party Recovery Complex Benefits
- May decrease acetaldehyde (the toxic metabolite of alcohol) in humans
- May improve lipid metabolism
- May lessen the effects of alcohol consumption
- May reduce oxidative stress on the liver after alcohol consumption
- N-Acetyl-L-Cysteine (NAC):
- May provide restorative effects to liver tissue after alcohol consumption
- May reduce the adverse after-effects of alcohol consumption
- Magnesium, Zinc, and Vitamin B12:
- Promotes replenishment of essential minerals and vitamins
Party Recovery Complex Benefits
Alcohol is metabolized after consumption into two enzymes: alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Alcohol must be broken down into these enzymes for the body to eliminate it. ADH then breaks down alcohol to acetaldehyde, which is a highly toxic substance. Then acetaldehyde is broken down into acetate, which is broken down into water and carbon dioxide, and eliminated from the body.
Acetaldehyde is the most toxic, carcinogenic byproduct of alcohol breakdown in the body. Alcohol is metabolized mostly in the liver but also in the pancreas, brain and, gastrointestinal tract. Acetaldehyde damages tissues in these areas while it waits to be broken down into acetate.
The body and liver can only metabolize alcohol at a certain rate, regardless of how much alcohol a person consumes. Body mass, liver size, and genetic variations regarding how efficiently the enzymes ADH and ALDH function, impact how fast alcohol can be metabolized.
- Dihydromyricetin (DHM) may decrease the amount of acetaldehyde in the human body. Although used for many years traditionally as Chinese medicine, scientific research on DHM and humans is scarce. DHM (Ampelopsin) is a flavonoid of the species Hovenia Dulcis, otherwise known as the Japanese Raisin Tree. The most conclusive scientific research about DHM and alcohol has been studied in animals and has shown promise in the capability of reducing the oxidative stress alcohol puts on the body and may be able to lessen the effects of acute alcohol consumption.
Hangovers are typical symptoms of fatigue, weakness, thirst, headache, muscle aches, nausea, vomiting, stomach pain, decreased sleep, vertigo, sensitivity to light, sensitivity to sound, decreased attention, decreased concentration, depression, anxiety, irritability, tremor, sweating, increased heart rate, and increased blood pressure. A hangover that you may experience may be a form of mild alcohol withdrawal, although hangovers differ from alcohol withdrawal in that they usually last a few hours rather than the several days associated with alcohol withdrawal. In each case, the hangover begins within several hours of the ending of the drinking when the blood alcohol concentration starts to fall.
- N-Acetyl-L-Cysteine (NAC) is an antioxidant and precursor for the master antioxidant glutathione. Its functions have been well studied in humans and can provide many benefits that extend beyond their interactions with alcohol. Unfortunately, scientific research with NAC, alcohol, and humans is scarce. In animal research, NAC has provided restorative effects to liver tissue after alcohol consumption and has demonstrated the possibility of reducing the after-effects of alcohol. Some theorize that the after-effects of alcohol NAC may reduce are the “hangovers” that people may experience, but since hangovers are such a subjective topic, it is still being studied.
The dehydration effect of alcohol causes an electrolyte imbalance. Consuming approximately 4 drinks causes the body to lose up to 1 quart of water over just a few hours.
Magnesium is an electrolyte and essential mineral responsible for supporting bone and heart health and participates in over 300 enzyme processes in the body. Magnesium is found in dietary sources–but a typical modern diet leaves approximately 68% of adults getting less than the recommended daily amount needed for the body’s processes.
- Alcohol depletes magnesium from the body right away–in responsible drinkers who consume only one drink to those who are chronic consumers of alcohol.
- Zinc is a trace element essential to the body
- Consumption of alcohol, especially chronic or heavy consumption of alcohol, leads to a deficiency, and alcohol decreases zinc absorption from dietary sources.
- Vitamin B12 is a vitamin necessary for cell integrity, DNA methylation, and synthesis of nucleotides.
- Moderate to heavy consumption of alcohol diminishes this vitamin.
Party Recovery Complex Mode of Action
Dihydromyricetin (DHM) is believed to involve GABA_a_R receptors and reduces oxidative stress through its high superoxide radical scavenging ability, as well as inhibiting lipid peroxidation.
N-Acetyl-L-Cysteine (NAC) is an acetylated form of L-Cysteine, and by supplementing with NAC, there is more L-cysteine available to replenish Glutathione.
When NAC is available to a cell, it is hydrolyzed to release the cysteine amino acid and then synthesized into GSH via enzymatic reactions with c-glutamylcysteine synthetase and GSH synthetase. Glutathione synthesis is limited by the number of substrates that are available for it. Glutathione’s main function is to provide antioxidant defense, modulate oxidation-reduction reaction signal transduction, detoxify electrophilic xenobiotics, store and transport cysteine, regulate cell proliferation and synthesis of deoxyribonucleotide synthesis, regulate leukotriene and prostaglandin metabolism, and regulate immune system responses.
Magnesium Bisglycinate Chelate is a chelated amino acid where 2 glycine molecules (bisglycinate) are attached to the magnesium molecule. The bisglycinate form is stable and avoids a breakdown in the gastrointestinal tract before it is completely absorbed. The bisglycinate chelate aids in mineral absorption because it is a small-sized molecule and can be absorbed directly by intestinal cells. The bisglycinate form of the mineral has one of the highest bioavailable absorptions.
Zinc Bisglycinate Chelate is a trace element that has a higher bioavailability than zinc gluconate and other forms of zinc supplements. Its structure of chelated amino acid means that there are 2 glycine molecules (bisglycinate) attached to the zinc molecule. The bisglycinate form is stable and avoids a breakdown in the gastrointestinal tract before it is completely absorbed. It is also tolerated better and has fewer gastrointestinal side effects. The bisglycinate chelate aids in mineral absorption because it is a small-sized molecule and can be absorbed directly by intestinal cells.
Party Recovery Complex Dosage
Party Recovery Complex provides 300 mg Dihydromyricetin, 300 mg N-Acetyl-L-Cysteine, 20 mg Zinc (as bisglycinate chelate), 24 mg Magnesium (as bisglycinate chelate), and 495 mcg Vitamin B12 (as methylcobalamin).
Suggested use for adults is to take 1 capsule by mouth before consuming alcohol.
Take 1 or 2 additional capsules after drinking, with a glass of water.